• Monterey 2019

Research and News From Members

Science Illustration

Short Peptides

Helical secondary and tertiary motifs are commonly observed as binding epitopes in natural and engineered protein scaffolds. While several strategies...


Aromatic Foldamer Hybrids

Translation, the mRNA-templated synthesis of peptides by the ribosome, can be manipulated to incorporate variants of the 20 cognate amino acids. Such approaches for expanding the range of chemical entities that can be produced by the ribosome may accelerate the discovery...

Image from the Hancock Lab

Immunomodulatory Activity

Synthetic peptides derived from naturally occurring host defence peptides, HDPs, have garnered significant attention as novel pharmaceuticals, particularly as alternatives to antibiotics and for immunomodulatory applications. One of the barriers to advancing synthetic peptides...

Scientific Diagram

Antimicrobial Peptides

To combat the serious issue of increasing global antibiotic resistance, new antimicrobial therapies are urgently required. As one alternative, previously used antibiotics are...

Scientific Graphic

Maintain or Break Symmetry

In coiled-coil, CC, protein structures α-helices wrap around one another to form rope-like assemblies. Most natural and designed CCs have two-four helices...

The McAlpine Group

Membrane Permeability

Published in Peptide Science, researchers in Shelli McAlpine's lab describe the design, synthesis, and biological evaluation of 5 N-methylated analogs that are based on a lead drug structure...

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Virtual Issue

Our Journal

To celebrate the 10th International Peptide Symposium in conjunction with the 55th Japanese Peptide Symposium, 3rd – 7th December, 2018, Kyoto, Japan, Peptide Science, ChemBioChem and ChemMedChem have prepared a joint Virtual Issue. These three Wiley journals publish top articles in peptide research and have selected some of their best for this special collection.  All the articles are free to read until March 2019....