Joel P. Schneider, Yixin Xie, and Tania L. Lopez-Silva at the National Cancer Institute, report a new positively charged azidoamino acid for strain-promoted azide–alkyne cycloaddition...

Human serum albumin, HSA, is the most abundant protein in human blood plasma. It plays a critical role in the native transportation of numerous drugs, metabolites, nutrients, and small molecules...

The family of NF-κB transcriptional activators controls the expression of many genes, including those involved in cell survival and development. The family consists of...

Researchers in the Del Valle Group, published in Organic Letters, report the total synthesis and configurational assignment of pargamicin A, a highly oxidized nonribosomal peptide...

Glycan-binding proteins, GBPs, are widely used reagents for basic research and clinical applications. These reagents allow for the identification and manipulation of glycan determinants...

In this article, published in Chemical Science, members of the James S. Nowick group show that the antibiotic teixobactin is a promising drug candidate...

In this article we show that stereoselective peptide catalysis is feasible in complex environments, including cell lysates...

Cancer is one of the leading causes of mortality in the world. Unfortunately, the present anticancer chemotherapeutics display high cytotoxicity...

Transforming growth factor-β (TGF-β) plays important roles in wound healing. The activity of TGF-β is initiated upon the binding of the growth factor...