Reflecting work in the Raj Lab
Understanding how proteins interact with biological metabolites is crucial for deciphering biological processes and advancing therapeutic strategies. This study focuses on a specific class of metabolites—α,β-unsaturated carbonyls, particularly acrolein-derived...
Reflecting work in the Deming Lab
Self-assembled polymeric vesicles that respond to biologically relevant stimuli have significant potential in drug delivery and synthetic biology. While many stimuli-responsive assemblies disassemble upon activation, invertible vesicles...
Reflecting work in the Suga & Vinogradov Labs
α,β-Dehydroalanine, ΔAla, is a highly reactive nonproteinogenic amino acid that serves as a versatile handle for modifying peptides, natural products, NPs, and proteins. While many ΔAla functionalization...
Reflecting work in the Phan Group
Ribosomally synthesized and post-translationally modified peptides, RiPPs, represent an expanding class of natural products distinguished by their extensive post-translational modifications. Among the enzymatic systems...
Reflecting work in the Hartrampf Lab
Solid-phase peptide synthesis, SPPS, and native chemical ligation, NCL, are powerful methods for obtaining peptides and proteins that are otherwise inaccessible...
Reflecting work in the Nowick Lab
Vancomycin, a cornerstone antibiotic for Gram-positive infections, faces diminishing efficacy due to the emergence of vancomycin-resistant Enterococci, VRE, and vancomycin-resistant...
Reflecting work in the Agarwal Lab
Brominated intermediates have long been favored in organic synthesis for their chemical versatility, particularly in transition-metal-assisted bond-forming reactions. The Agarwal and van der Donk study represents a significant leap...
Reflecting work in the NSF CGEM
The ability to precisely manipulate the peptide backbone remains one of the fundamental challenges in biomolecular engineering. While ribosomal translation and peptide synthesis methods allow for modifications...
Reflecting work in the Guha Lab
Researchers in the Samit Guha Group at Jadavpur University, Kolkata, India, published in Bioconjugate Chemistry, report a groundbreaking approach to cancer imaging...
Reflecting work in the Liu Group
To address the limitations of current methods for peptide macrocyclization, which often rely on nonspecific small-molecule linkers...
Reflecting work in the Woolfson and Oliver Labs
To address the formidable challenge of binding and orienting multiple small molecules for directed chemical reactions, researchers in the Woolfson and Oliver groups at the University of Bristol, published in...
Reflecting work in the Knudsen Group
Researchers in the Knudsen Group at the University of Aarhus, Denmark, published in Biochemistry, report the construction of a Saccharomyces cerevisiae-specific SICLOPPS library of 80 million members...
Reflecting work in the Proulx Lab
Published in the Journal of the American Chemical Society, researchers in the Proulx group at the North Carolina State University at Raleigh, present the first approach to controlled metal chelation of peptide backbones...
Reflecting work in the Ding Lab
Published in ACS Chemical Biology, researchers in the Ding Group at the University of Florida, reconstructed prunipeptin biosynthesis from Streptomyces coelicolor...
Reflecting work in the Payne Lab
Chemokines are small proteins involved in recruiting leukocytes to sites of inflammation via interactions with specific cell surface receptors. CCL22 is a chemokine known to play a critical role in...
Reflecting work in the Schultz Lab
Nicotinamide-containing cofactors play an essential role in many enzymes that catalyze two-electron redox reactions. However, it is difficult to engineer nicotinamide binding sites into proteins due to the extended nature...
Reflecting work in the Baiz Lab
Biomolecular condensates provide a mechanism for compartmentalization of biomolecules in eukaryotic cells. These liquid-like condensates are formed via liquid–liquid phase separation
Reflecting work in the Del Valle and Ebright Groups
Members of the Del Valle Group at the University of Notre Dame, in collaboration with the Ebright Group at Rutgers, report in Organic letters, the synthesis of the antimicrobial cyclodepsipeptides...
Women in Peptide Science
On February 11th, the world celebrates the International Day of Women and Girls in Science, a day dedicated to promoting full and equal access to and participation in science for women and girls. This observance highlights the critical role women play in science and technology communities and emphasizes the need to strengthen their participation.
In the field of peptide science, women have made significant contributions, advancing our understanding of peptides and their applications. The American Peptide Society, APS, has recognized several outstanding female scientists over the past five years for their exceptional work.
Peptide Purification
In this sponsored content by Gyros Protein Technologies, learn how to remove impurities faster with less solvent consumption using catch-and-release technology.
Peptide-related impurities can significantly influence the outcome of drug research and development, for example, false-positive results, and must be removed to ensure high assay reliability.
Ultimately, such impurities must be removed entirely from active pharmaceutical ingredients to provide the highest quality clinical-grade material. This article tells you how.
What Current Members Say
"My membership in the American Peptide Society and participation in the biennial APS Symposia has fostered scientific collaborations with trailblazing scientists from academia and industry, who are pushing the boundaries of peptide and protein chemistry into new scientific arenas. The strongly diverse, inclusive and welcoming aspects of the APS have and will continue to provide a great opportunity for the education and professional development of young peptide scientists from all over the world."
Champak Chatterjee
Professor, Department of Chemistry
University of Washington
"The American Peptide Society is at the forefront of showcasing innovative research and emerging trends in the field. The symposiums are a combination of inspiration and knowledge, essential for all peptide enthusiasts in academia and pharma to stay ahead in peptide science."
Danny Chou
Assistant Professor of Pediatrics Endocrinology
Stanford University, School of Medicine
"The APS has been an integral part of my PhD experience. Between introducing me to a broad array of peptide science, allowing me to meet and develop relationships with colleagues near and far, and providing me with the opportunity to present, discuss, and get feedback on my own research, APS has provided a foundation for the beginning of my career."
Zoë Adams
Ph.D. - Postdoctoral Research Fellow
Scripps Research
Peptide Synthesis for Beginners
Explore this in-depth tutorial on peptide synthesis, featuring contributions from the APS Website Committee and other researchers in the field. This tutorial offers a thorough examination of key concepts and techniques in peptide synthesis, supported by engaging video content.
Free Membership
Membership is free and open to graduate and undergraduate students, postdocs, professionals, and retired professionals, with an interest in peptides or a related scientific field.