Reflecting work in the Agarwal Lab
Brominated intermediates have long been favored in organic synthesis for their chemical versatility, particularly in transition-metal-assisted bond-forming reactions. The Agarwal and van der Donk study represents a significant leap...
Reflecting work in the NSF CGEM
The ability to precisely manipulate the peptide backbone remains one of the fundamental challenges in biomolecular engineering. While ribosomal translation and peptide synthesis methods allow for modifications...
Reflecting work in the Guha Lab
Researchers in the Samit Guha Group at Jadavpur University, Kolkata, India, published in Bioconjugate Chemistry, report a groundbreaking approach to cancer imaging...
Reflecting work in the Liu Group
To address the limitations of current methods for peptide macrocyclization, which often rely on nonspecific small-molecule linkers...
Reflecting work in the Woolfson and Oliver Labs
To address the formidable challenge of binding and orienting multiple small molecules for directed chemical reactions, researchers in the Woolfson and Oliver groups at the University of Bristol, published in...
Reflecting work in the Knudsen Group
Researchers in the Knudsen Group at the University of Aarhus, Denmark, published in Biochemistry, report the construction of a Saccharomyces cerevisiae-specific SICLOPPS library of 80 million members...
Reflecting work in the Proulx Lab
Published in the Journal of the American Chemical Society, researchers in the Proulx group at the North Carolina State University at Raleigh, present the first approach to controlled metal chelation of peptide backbones...
Reflecting work in the Ding Lab
Published in ACS Chemical Biology, researchers in the Ding Group at the University of Florida, reconstructed prunipeptin biosynthesis from Streptomyces coelicolor...
Reflecting work in the Payne Lab
Chemokines are small proteins involved in recruiting leukocytes to sites of inflammation via interactions with specific cell surface receptors. CCL22 is a chemokine known to play a critical role in...
Reflecting work in the Schultz Lab
Nicotinamide-containing cofactors play an essential role in many enzymes that catalyze two-electron redox reactions. However, it is difficult to engineer nicotinamide binding sites into proteins due to the extended nature...
Reflecting work in the Baiz Lab
Biomolecular condensates provide a mechanism for compartmentalization of biomolecules in eukaryotic cells. These liquid-like condensates are formed via liquid–liquid phase separation
Reflecting work in the Del Valle and Ebright Groups
Members of the Del Valle Group at the University of Notre Dame, in collaboration with the Ebright Group at Rutgers, report in Organic letters, the synthesis of the antimicrobial cyclodepsipeptides...
Reflecting work in the The Futaki Lab
Published in Bioconjugate Chemistry, researchers from Shiroh Futaki Group at the Kyoto University, prepared conjugates of the biocompatible polysaccharide pullulan with a cell membrane permeabilizing peptide...
Reflecting work in the The Raines Group
As a traceless, bioreversible modification, the esterification of carboxyl groups in peptides and proteins has the potential to increase their clinical utility. An impediment is the lack of strategies to quantify...
Reflecting work in the The Mapp Group
The melanocortin-3 receptor, MC3R, is a G-protein coupled receptor that regulates appetite and is a potential therapeutic target for anorexia and weight loss treatments...
Reflecting work in the Suga and Goto Groups
Prenylation of peptides is widely observed in the secondary metabolites of diverse organisms, granting peptides unique chemical properties distinct from proteinogenic amino acids. Discovery of...
Reflecting work in the Yudin Lab
Helical secondary structures, namely α- and 310-helices, comprise >60% of all secondary structures observed at protein–protein interactions, PPIs, and are responsible for the mediation of many biological...
Reflecting work in the Wennemers Lab
In a study from the Wennemers Lab at ETH, Zūrich, published in JACS, group members present an organocatalytic kinetic resolution to yield enantiomerically enriched β-branched aldehydes and γ-nitroaldehydes with three...
Women in Peptide Science
On February 11th, the world celebrates the International Day of Women and Girls in Science, a day dedicated to promoting full and equal access to and participation in science for women and girls. This observance highlights the critical role women play in science and technology communities and emphasizes the need to strengthen their participation.
In the field of peptide science, women have made significant contributions, advancing our understanding of peptides and their applications. The American Peptide Society, APS, has recognized several outstanding female scientists over the past five years for their exceptional work.
Peptide Purification
In this sponsored content by Gyros Protein Technologies, learn how to remove impurities faster with less solvent consumption using catch-and-release technology.
Peptide-related impurities can significantly influence the outcome of drug research and development, for example, false-positive results, and must be removed to ensure high assay reliability.
Ultimately, such impurities must be removed entirely from active pharmaceutical ingredients to provide the highest quality clinical-grade material. This article tells you how.
What Current Members Say
“APS provides a forum for connecting graduate students, postdocs and working professionals with each other based on shared professional skills and interests. When it comes time to look for their next position, APS members can count on a strong network of like-minded scientists who value their skills and accomplishments.”
Joshua Kritzer
Professor
Tufts University
"My membership in the American Peptide Society and participation in the biennial APS Symposia has fostered scientific collaborations with trailblazing scientists from academia and industry, who are pushing the boundaries of peptide and protein chemistry into new scientific arenas. The strongly diverse, inclusive and welcoming aspects of the APS have and will continue to provide a great opportunity for the education and professional development of young peptide scientists from all over the world."
Champak Chatterjee
Professor, Department of Chemistry
University of Washington
"The American Peptide Society is at the forefront of showcasing innovative research and emerging trends in the field. The symposiums are a combination of inspiration and knowledge, essential for all peptide enthusiasts in academia and pharma to stay ahead in peptide science."
Danny Chou
Assistant Professor of Pediatrics Endocrinology
Stanford University, School of Medicine
Peptide Synthesis for Beginners
Explore this in-depth tutorial on peptide synthesis, featuring contributions from the APS Website Committee and other researchers in the field. This tutorial offers a thorough examination of key concepts and techniques in peptide synthesis, supported by engaging video content.
Free Membership
Membership is free and open to graduate and undergraduate students, postdocs, professionals, and retired professionals, with an interest in peptides or a related scientific field.