Peptide Publications Archive

Versatile Precursors

Mitchell Lab

Cyclopropane-containing amino acids, prized for their conformational rigidity and stability, are of increasing interest in therapeutic peptide development and antimicrobial drug discovery. A recent study …

Selective Coupling

Suga Lab

α,β-Dehydroalanine, ΔAla, is a highly reactive nonproteinogenic amino acid that serves as a versatile handle for modifying peptides, natural products, NPs, and proteins. While many …

Synthesis Tag

Hartrampf Lab

Solid-phase peptide synthesis, SPPS, and native chemical ligation, NCL, are powerful methods for obtaining peptides and proteins that are otherwise inaccessible...

Backbone Editing

Schepartz Lab

The ability to precisely manipulate the peptide backbone remains one of the fundamental challenges in biomolecular engineering. While ribosomal translation and peptide synthesis methods allow …

Metallo-Azapeptides

Proulx Lab

Published in the Journal of the American Chemical Society, researchers in the Proulx group at the North Carolina State University at Raleigh, present the …