Peptide Publications Archive
Oxidative Peptide Coupling
Proulx Lab
This study demonstrates that a key determinant of this reactivity is the choice of solvent. By shifting from aqueous buffer to a mixed organic solvent …
Molecular Scaffolds
Craik Lab
This comprehensive review from the labs of David Craik and Lara Malins at Australian Research Council Centre of Excellence for Innovations in Peptide and Protein …
Quorum Sensing
Tal-Gan Lab
Streptococcus cristatus, a commensal member of the oral microbiota and recently reclassified from Streptococcus oligofermentans, has emerged as a promising candidate in the …
From Hydrogel to Crystal
Schneider Lab
Published in the Journal of the American Chemical Society, researchers in the lab of Dr. Joel P. Schneider at NIH, have unveiled a groundbreaking …
Sequence Architecture
Woolfson Lab
The Woolfson Lab continues to break new ground in de novo protein design with the successful creation of mixed-charge A3B3 heterohexameric α-helical …
Versatile Precursors
Mitchell Lab
Cyclopropane-containing amino acids, prized for their conformational rigidity and stability, are of increasing interest in therapeutic peptide development and antimicrobial drug discovery. A recent study …
Ubiquitin Azapeptide Esters
Liu Lab
Published as an ASAP article in the Journal of the American Chemical Society, researchers from the Wenshe Liu Lab at Texas A&M, currenly our …
Capturing the Uncatchable
Arora Lab
In a major step forward, researchers in the Arora Group at the New York University, have now developed a rationally designed proteomimetic receptor capable of …
Dynamic Ion Channels
Niitsu Lab
Membrane-spanning peptides that form ion-conductive channels remain a challenging frontier in de novo protein design. While strides have been made in creating water-soluble peptide assemblies, …
Antimicrobial Peptide
D'Amelio Lab
As antibiotic resistance surges worldwide, the search for effective new therapeutics has led scientists to a surprising source: the venom of Bungarus fasciatus, the …
Protein Design
Tezcan Lab
Isopeptide bonds, IPBs, — covalent linkages between the side chains of lysine and asparagine/glutamine or aspartate/glutamate — are remarkable for their chemical resilience and structural …
Enlicitide Decanoate
Thaisrivongs Lab
The total synthesis and process development of enlicitide decanoate, MK-0616, an orally bioavailable inhibitor of proprotein convertase subtilisin/kexin type 9, PCSK9, represents a major breakthrough …