Peptide Publications Archive

Iodo Quantification

Iodo Quantification

Lilienkampf Lab

In work published in ACS Chemical Biology, David J. Clarke, Annamaria Lilienkampf, and collaborators from the University of Edinburgh, introduce an iodo based labeling strategy …

Docking Bias

Docking Bias

Keating Lab

Deep-learning structure predictors now place many peptides correctly onto their protein partners, and this recent work from Lindsey Guan and Amy Keating at the Massachusetts …

Dilp Divergence

Dilp Divergence

Bland Lab

Insulin-like peptides orchestrate how animals apportion nutrients between storage and growth, yet distinct ligands may encode different cues even when signaling through a single receptor. …

Sequence Hydrophobicity

Sequence Hydrophobicity

Perry Lab

In this study, published in Biomacromolecules, researchers in Sarah Perry's group at the University of Massachusetts - Amherst, employ sequence-defined polypeptides as minimal models …

Affinity Landscapes

Affinity Landscapes

Bussemaker Lab

A collaborative study from the Bussemaker and Shah Groups at Columbia University, published in Protein Science, establishes an integrated experimental–computational framework, built on massively …

Alkyne Grasp

Alkyne Grasp

Fujishiro Lab

ATP-grasp ligases offer a powerful route to diversify peptide structures, and BesA stands out for its ability to incorporate terminal alkyne groups into dipeptides with …

Aquaporin Bridge

Aquaporin Bridge

Wang Lab

Researchers from the Wang Group at the School of Life Sciences, Shandong University, China, report in PNAS a mechanistic bridge between two pillars of arthropod …

Peptide Portals

Peptide Portals

Otto Lab

For decades, antimicrobial peptides, AMPs, have stood at the crossroads between innate immunity and drug discovery, yet their molecular diversity remains incompletely explored. Dickey, Otto, …

Glycan–Metal Synergy

Glycan–Metal Synergy

Koksch Lab

Hydrogels, highly hydrated polymer networks, underpin both natural barriers such as mucus and numerous biomedical applications. Mucins, the glycoprotein constituents of mucus, achieve their viscoelasticity …

Phosphine Rebridging

Phosphine Rebridging

Hackenberger Lab

Published in Angewandte Chemie International Editition, researchers from the Hackenberger Lab at the Humboldt-Universität in Berlin, present a powerful new class of phosphine oxide–based …

Helical Hydrazides

Helical Hydrazides

Gellman Lab

Seeking to understand the relative kinetic benefits of reactive unit connection and preorganization, researchers from the Gellman Lab at the University of Wisconsin–Madison investigated α/β-peptide …

Serine Switch

Serine Switch

Diao Lab

Published in the Journal of the American Chemical Society, work by first author Zhenyan Guo in the Diao Lab at the New York University, …